Do you know your genotype and its compatibility, phenotype, blood group and your genetic health?

The genotype is the genetic makeup of an organism and the genetic makeup of an organism is coded for in its DNA, being the hereditary material of the cell.

Medical researches have revealed that the DNA of organisms is organized into sections that code for proteins which are called genes.

Understand that each gene has different versions and the specific version that an organism inherits is its genotype. It is the genotype of an organism that helps to control the phenotype, or the observable traits of that organism.

What are the examples of phenotypes? It include hair color (whether brown, black, blonde), eye color, or even microscopic traits such as which version of a protein is produced inside cells.

How Genotypes, Blood Groups And Phenotypes Are Inherited

Genotypes and blood groups are inherited from parents. There are about 41 types of blood groups according to ISBT in 2019, especially the Rh group and ABO systems.

Within the Rh and ABO blood group systems, there are 8 different phenotypes in human blood – A-Positive, B-Positive, A-Negative, B-Negative, AB-Positive, AB-Negative, O-Positive, and O-Negative.

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The genotype helps to indicate the protein type that is found in the red blood cells (RBCs). People who possess the genotypes SS and SC have sickle cell diseases and based on the type of haemoglobin found in the RBCs, human beings have about six genotypes namely: – AA, AC, AS, CC, SC, and SS.

DNA is the genetic material of the cell in human bodies which is arranged in order of sequences called genes.

Human genes come in different versions called alleles. Allele is one of two or more versions of DNA sequence at a particular genomic location.

Each individual inherits two alleles, one from each parent, for a particular genomic location where the type of variation exists. There are two copies of each gene in an individual and the specific combination of alleles which is inherited is called the genotype.

Study shows that alleles can also be dominant if they mask another allele, or recessive. If you inherit two dominant alleles (LL) your genotype is homozygous dominant. But if it is two recessive alleles (ll) your genotype is homozygous recessive.

In any case an individual inherits one of each allele (Ll) the genotype will be heterozygous.

What Are Differences Between Blood Group And Genotype?

The major difference between blood group and genotype is that blood group is what constitutes the different kinds of blood found in human beings, governed by different antigens found on the surface of the red blood cells (RBCs), while genotype forms the genetic constituency of cells in human beings.

Blood Group

It is important to know that the absence or presence of antibodies and inherited antigenic particles on the surface of the red blood cells (RBCs) leads to the classification of humans’ blood into different groups.

The following are the antigens based on the blood group system: Carbohydrates, proteins, and glycoproteins.

Also note that a few of these antigens are found on the surface of the other cell types of different tissues.

According to Study.com, “There are two main types of genotypes, heterozygous and homozygous. If an organism has a heterozygous genotype, this means they inherit two different versions of a gene. If an organism is homozygous for a gene, it means they inherit two of the same versions of the gene.”

As explained earlier, human beings can inherit a version of blood that produces A-type of blood, B-type of blood, or o-type of blood.

The Following Are Some Examples Of Heterozygous And Homozygous Genotypes

Heterozygous genotypes: Ao, AB, or Bo.

Homozygous genotypes for blood type: AA, BB, or oo.

Research shows that different genotypes produce different phenotypes depending on which version is dominant to the other.

Function Of Genotype And Compatibilities

Genotypes makes up for the genetic constitution of each individual.

Your genotype makes up for the entire heritable genetic identity you possess– the genes transferred from your parent to you, which you also transfer to your children, the children’s children throughout generations.

It is the red blood cells (RBCs) that is involved in determining the genotype of human beings.

Understanding the genotypes compatibilities can prevent the hardships caused by Sickle Cell Disease (SCD) in relationships and families, ensuring healthier generations to come.

The genotypes compatibilities:

• AA + AA: No risk of Sickle Cell Disease
• AA + AS: Safe, but potential carrier of the sickle cell trait
• AS + AS: 25% risk of having a child with SCD
• AS + SS / SS + SS: High risk of having a child with SCD

Take the step today—know your genotype and secure a brighter future for yourself and your family.

After twenty-seven years of marriage, Bill and Melinda Gates, one of the most powerful couples in the world, has announced that they are divorcing. Making the announcement on Twitter, the joint statement read that “After a great deal of thought and a lot of work on our relationship, we have made the decision to end our marriage.”

“The most famous and wealthiest are not the happiest in marriage” ~ Pst. Maxwell Ekene Nnawuihe

The philanthropists said in the statement that they planned to continue to work together on the Bill and Melinda Gates Foundation.

Bill and Melinda married in 1994, seven years after Melinda Gates joined Microsoft as a product manager. When Bill Gates initially asked her out, he inquired if they could go out “two weeks from tonight.”

Melinda Gates said: “I have no idea what I’m doing two weeks from tonight.” Bill Gates responded: “You’re not spontaneous enough for me.” After taking her number, he ended up calling her that same day.

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They have three children together, including one who is a nationally ranked equestrian show jumper. Each of the Gates children will inherit $10 million, Bill Gates has said, and the rest of the Gates’ fortune will go to charity.

About the time that the pair met, Microsoft had a market capitalization of about $35 billion. Now, that figure is almost $2 trillion, and Microsoft is one of the most valuable companies.

Bill Gates has an estimated net worth of $124 billion, which grew from $98 billion in 2020, according to Forbes. He is No. 4 on the outlet’s ranking of the world’s billionaires .

Forbes named Melinda Gates one of the most powerful women in philanthropy, placing her at the No. 5 spot on its “Power Women 2020” list. Melinda Gates has changed her Twitter-profile name to Melinda French Gates, incorporating her maiden name into the moniker.

The Gates’ have long said they will spend their fortune on philanthropic causes, particularly through the Bill and Melinda Gate Foundation. They launched the organization in 2000 and have given billions to global health, poverty, and education.

The Bill and Melinda Gates Foundation has donated upward of $250 million to coronavirus-response efforts since the pandemic began in March 2020.

A spokesperson from the foundation told Insider in an email that Bill and Melinda Gates will remain co-chairs and trustees of the organization and will continue to work together. No changes are planned for their roles in light of the news of their divorce.

In 2010, they launched The Giving Pledge with the billionaire investor Warren Buffett , a commitment to give most of their wealth to charity during their lifetime or pledge to do so after their death.

Details about the divorce are unclear, but the resulting settlement could be one of the largest ever. When Amazon CEO Jeff Bezos and his wife, MacKenzie, split up in 2019, their settlement was $38 billion . The settlement made MacKenzie Scott the third-wealthiest woman.

The Gates’ split is likely to lead to questions from those in the nonprofit world wondering how, if at all, the foundation’s decision-making around investments will be affected.

Mrs. Regina Fani-Kayode, the first wife of a former Aviation Minister, Femi Fani-Kayode, has released and official statement on Precious Chikwendu, ex-wife of Femi Fani-Kayode.

In defense of her husband, Mr. Fani-Kayode, she described Precious Chikwendu and her family as hungry refugees and ungrateful to the goodwill and comfort Femi Fani-Kayode lavished on both her and her family.

Mrs. Fani-Kayode berated Precious Chikwendu for sleeping with her husband’s male friends.

In her words: “All his male friends you have been offering your body to have already confessed so please stop trying to blackmail them”.

Read her statement in full:

“My name is Mrs. Regina Fani-Kayode and I am the first wife of Chief Femi Fani-Kayode. We were married in 1997 and we are still married up until today.

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“Precious Chikwendu, a strange woman that he took under his roof, married under law and custom and lived with for seven years has written things about my husband which are not only untrue but also downright defamatory and scandalous and I will respond to her with the following as a first salvo.

“Precious, you are just a sick woman and a big liar. I know you collected over half a million USD dollars from Femi within the first few months of meeting him for a fake investment. We have witnesses to prove it and remember that you even asked me to thank him for it. I also know he set you up in one business or the other four times in 7 years and got you offices etc. but you squandered it all.

“When you came to my husband and took over my home you and your family were like hungry refugees. You had nothing but rubber slippers and you were desperate for help. My husband sent three of your siblings to the highest schools for seven years and took care of their every need yet you now slander him and insult him not minding the effect it will have on your own children. That in itself proves that you are insane.

“You say he has mental issues meanwhile you were the one that was locked up in a mental hospital for one month after trying to kill him and his children. How could you have stayed in the home of a man with mental problems for six good years and allowed your mother, aunty, two brothers and sisters to stay there too? Who are you trying to fool? You are nothing but a wretched ingrate and, like Madame Kemi Olunloyo said, a pathological liar. And God will punish you and all your siblings for your ingratitude and lies.

“You knew he was still married to me because you and I spoke countless times on the phone and you even stayed in my room and wore my clothes . You had nothing when he took you in, you are so ungrateful. 6 of your relatives lived in my house for 6 yrs and they were all depending on Femi for food , upkeep, medical bills and school fees. Even your sister’s wedding was paid for by him .

“But that didn’t stop you from plotting with your gang to kill him. You admitted to me about being naked in the hotel room with a man on the night FFK caught you. I know the huge amounts of money he spent on you and your family and I’m sure you can’t deny that, that’s why his friends tagged you as a gold digger.

“Your inability to love your children which you attributed to a medical condition was well tolerated by FFK and twelve nannies and nurses were working round the clock to keep you from harming them but you still got to beat up Aragon badly and bleached their skins till they broke out in sores. You are a mother from hell and a horrible woman. In one of your dramatic fits, you pulled knifes to stab Femi and the children and police were called in stop you.

“FFK never laid hands on you, even on the day he caught you in the hotel room with your lover. Is that the act of a violent man ?

“All his male friends you have been offering your body to have already confessed so please stop trying to blackmail them. Stop working for those criminals who are just using your body to rip off rich men. There is so much more to expose about your wickedness but I really don’t have time for your drama this year.

“I am the reason Femi tolerated your nonsense for so long but enough is enough, I will not allow you to kill him because of your greed. He’s too busy to answer your stupid tantrums and fantastic lies, your media rants lack facts and the powerful truth will always prevail.

“Your constant threats to kill the children is why Femi is afraid to leave them with you, you can’t even find the time to call them till now.

“You think raining insults daily on their nannies is the best way to encourage them, instead of talking to your babies. And why were you stealing half their salaries when you had your own allowance ? All the evidence will be presented in court soon”.

(Mrs. Regina Fani-Kayode, 13th March 2021)